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Surface Proteins and Exotoxins Are Required for the Pathogenesis of Staphylococcus aureusPneumonia

Authors :
Wardenburg, Juliane Bubeck
Patel, Ravi J.
Schneewind, Olaf
Source :
Infection and Immunity; February 2007, Vol. 75 Issue: 2 p1040-1044, 5p
Publication Year :
2007

Abstract

ABSTRACTA model of Staphylococcus aureus-induced pneumonia in adult, immunocompetent C57BL/6J mice is described. This model closely mimics the clinical and pathological features of pneumonia in human patients. Using this system, we defined a role for S. aureusstrain Newman surface proteins and secreted exotoxins in pneumonia-related mortality.

Details

Language :
English
ISSN :
00199567 and 10985522
Volume :
75
Issue :
2
Database :
Supplemental Index
Journal :
Infection and Immunity
Publication Type :
Periodical
Accession number :
ejs57559143
Full Text :
https://doi.org/10.1128/IAI.01313-06