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Protection of Mice against Plasmodium yoeliiSporozoite Challenge with P. yoeliiMerozoite Surface Protein 1 DNA Vaccines
- Source :
- Infection and Immunity; July 1998, Vol. 66 Issue: 7 p3457-3461, 5p
- Publication Year :
- 1998
-
Abstract
- ABSTRACTImmunization of mice with DNA vaccines encoding the full-length form and C and N termini of Plasmodium yoeliimerozoite surface protein 1 provided partial protection against sporozoite challenge and resulted in boosting of antibody titers after challenge. In C57BL/6 mice, two DNA vaccines provided protection comparable to that of recombinant protein consisting of the C terminus in Freund’s adjuvant.
Details
- Language :
- English
- ISSN :
- 00199567 and 10985522
- Volume :
- 66
- Issue :
- 7
- Database :
- Supplemental Index
- Journal :
- Infection and Immunity
- Publication Type :
- Periodical
- Accession number :
- ejs57552449
- Full Text :
- https://doi.org/10.1128/IAI.66.7.3457-3461.1998