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Induction of interferon synthesis in mice by fractions from Nocardia
- Source :
- Infection and Immunity; February 1978, Vol. 19 Issue: 2 p353-356, 4p
- Publication Year :
- 1978
-
Abstract
- Three fractions of Nocardia, Nocardia water-soluble mitogen (NWSM), Nocardia water-soluble mitogen pellet (NWSMP), and the cell wall peptidoglycan, which are mitogenic for B lymphocytes, were able to induce circulating interferon in mice, NWSMP and NWSM being the most active. The peak of interferon appeared about 2 h after injection. The interferon induced by NSWMP and NWSM was acid stable and antigenically related to viral interferon, as shown by neutralization with antibodies directed against Newcastle disease virus-induced interferon.
Details
- Language :
- English
- ISSN :
- 00199567 and 10985522
- Volume :
- 19
- Issue :
- 2
- Database :
- Supplemental Index
- Journal :
- Infection and Immunity
- Publication Type :
- Periodical
- Accession number :
- ejs57533324
- Full Text :
- https://doi.org/10.1128/iai.19.2.353-356.1978