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Characterization of Plasmodium vivaxHeat Shock Protein 70 and Evaluation of Its Value for Serodiagnosis of Tertian Malaria
- Source :
- Clinical and Vaccine Immunology (formerly CDLI); March 2007, Vol. 14 Issue: 3 p320-322, 3p
- Publication Year :
- 2007
-
Abstract
- ABSTRACTWe have characterized Plasmodium vivaxheat shock protein 70 (PvHSP70) and evaluated serodiagnostic applicability of recombinant PvHSP70 (rPvHSP70). In enzyme-linked immunosorbent assays and immunoblot analyses, rPvHSP70 showed high sensitivity (88.8%; 203/228 cases). P. falciparum-infected sera revealed positive reactions (78.8%). The predominant immunoglobulin G (IgG) subclasses were segregated with IgG1 and IgG3.
Details
- Language :
- English
- ISSN :
- 15566811 and 1556679X
- Volume :
- 14
- Issue :
- 3
- Database :
- Supplemental Index
- Journal :
- Clinical and Vaccine Immunology (formerly CDLI)
- Publication Type :
- Periodical
- Accession number :
- ejs57509809
- Full Text :
- https://doi.org/10.1128/CVI.00424-06