West Nile and St. Louis Encephalitis Virus Antibody Seroconversion, Prevalence, and Persistence in Naturally Infected Pig-Tailed Macaques (Macaca nemestrina)

Authors :: Hukkanen, Renee R.
Liggitt, H. Denny
Kelley, Stephen T.
Grant, Richard
Anderson, David M.
Hall, Roy A.
Tesh, Robert B.
Travassos DaRosa, Amelia P.
Bielefeldt-Ohmann, Helle
Source :: Clinical and Vaccine Immunology (formerly CDLI); June 2006, Vol. 13 Issue: 6 p711-714, 4p
Publication Year :: 2006
Abstract: ABSTRACTPig-tailed macaques (Macaca nemestrina) naturally infected with West Nile virus were monitored from 1999 to 2005 to determine virus-specific antibody seroconversion, prevalence, and persistence. Antibodies persisted for up to 36 months, as detected by epitope-blocking enzyme-linked immunosorbent and hemagglutination inhibition assays. Exposure to cocirculating St. Louis encephalitis virus was evaluated by Western blotting and immunofluorescence assays.

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