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Association of varicose veins with rare protein-truncating variants in PIEZO1identified by exome sequencing of a large clinical population

Authors :
Smelser, Diane T.
Haley, Jeremy S.
Ryer, Evan J.
Elmore, James R.
Cook, Adam M.
Carey, David J.
Source :
Journal of Vascular Surgery: Venous and Lymphatic Disorders; 20210101, Issue: Preprints
Publication Year :
2021

Abstract

The present study sought to determine whether protein-truncating variants (PTVs) in PIEZO1and CASZ1genes, previously shown to be associated with varicose veins, were associated with an altered risk of varicose veins.

Details

Language :
English
ISSN :
2213333X
Issue :
Preprints
Database :
Supplemental Index
Journal :
Journal of Vascular Surgery: Venous and Lymphatic Disorders
Publication Type :
Periodical
Accession number :
ejs57300451
Full Text :
https://doi.org/10.1016/j.jvsv.2021.07.007