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In Vitro Activities of 10 Combinations of Antifungal Agents against the Multiresistant Pathogen Scopulariopsis brevicaulis

Authors :
Cuenca-Estrella, Manuel
Gomez-Lopez, Alicia
Buitrago, Maria J.
Mellado, Emilia
Garcia-Effron, Guillermo
Rodriguez-Tudela, Juan L.
Source :
Antimicrobial Agents and Chemotherapy; June 2006, Vol. 50 Issue: 6 p2248-2250, 3p
Publication Year :
2006

Abstract

ABSTRACTThe activities of 10 combinations of antifungal agents against 25 clinical isolates of Scopulariopsis brevicauliswere tested by the checkerboard technique. An average indifferent effect was detected for all combinations. Synergy was observed for some isolates and combinations, particularly with posaconazole-terbinafine (68% of strains), amphotericin B-caspofungin (60%), and posaconazole-caspofungin (48%).

Details

Language :
English
ISSN :
00664804 and 10986596
Volume :
50
Issue :
6
Database :
Supplemental Index
Journal :
Antimicrobial Agents and Chemotherapy
Publication Type :
Periodical
Accession number :
ejs57151006
Full Text :
https://doi.org/10.1128/AAC.00162-06