Back to Search Start Over

Characterization of Plasmids Carrying CMY-2 from Expanded-Spectrum Cephalosporin-Resistant SalmonellaStrains Isolated in the United States between 1996 and 1998

Authors :
Carattoli, A.
Tosini, F.
Giles, W. P.
Rupp, M. E.
Hinrichs, S. H.
Angulo, F. J.
Barrett, T. J.
Fey, P. D.
Source :
Antimicrobial Agents and Chemotherapy; May 2002, Vol. 46 Issue: 5 p1269-1272, 4p
Publication Year :
2002

Abstract

ABSTRACTSequencing of DNA from 15 expanded-spectrum cephalosporin (e.g., ceftriaxone)-resistant Salmonellaisolates obtained in the United States revealed that resistance to ceftriaxone in all isolates was mediated by cmy-2.Hybridization patterns revealed three plasmid structures containing cmy-2in these 15 isolates. These data suggest that the spread of cmy-2among Salmonellastrains is occurring through mobilization of the cmy-2gene into different plasmid backbones and consequent horizontal transfer by conjugation.

Details

Language :
English
ISSN :
00664804 and 10986596
Volume :
46
Issue :
5
Database :
Supplemental Index
Journal :
Antimicrobial Agents and Chemotherapy
Publication Type :
Periodical
Accession number :
ejs57148462
Full Text :
https://doi.org/10.1128/AAC.46.5.1269-1272.2002