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Ginsenoside Rb1 attenuates methamphetamine (METH)-induced neurotoxicity through the NR2B/ERK/CREB/BDNF signalings in vitroand in vivomodels
- Source :
- Journal of Ginseng Research; 20210101, Issue: Preprints
- Publication Year :
- 2021
-
Abstract
- This study investigates the effects of ginsenoside Rb1 (GsRb1) on methamphetamine (METH)-induced toxicity in SH-SY5Y neuroblastoma cells and METH-induced conditioned place preference (CPP) in adult Sprague-Dawley rats. It also examines whether GsRb1 can regulate these effects through the NR2B/ERK/CREB/BDNF signaling pathways.
Details
- Language :
- English
- ISSN :
- 12268453 and 20934947
- Issue :
- Preprints
- Database :
- Supplemental Index
- Journal :
- Journal of Ginseng Research
- Publication Type :
- Periodical
- Accession number :
- ejs57080284
- Full Text :
- https://doi.org/10.1016/j.jgr.2021.07.005