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Platelet and Red Blood Cell Transfusions and Risk of Acute Graft-versus-Host Disease after Myeloablative Allogeneic Hematopoietic Cell Transplantation

Authors :
Gjærde, Lars Klingen
Sørensen, Anne Louise Tølbøll
von Stemann, Jakob Hjorth
Fischer-Nielsen, Anne
Hansen, Morten Bagge
Sengeløv, Henrik
Ostrowski, Sisse Rye
Source :
Transplantation and Cellular Therapy; 20210101, Issue: Preprints
Publication Year :
2021

Abstract

•Platelet and RBC transfusions early after allo-HCT were associated with aGVHD.•Blood donor age, sex, and product storage time did not influence these associations.•Transfusions were positively correlated with plasma levels of TNF-α, IL-6, and thrombomodulin.

Details

Language :
English
ISSN :
26666375 and 26666367
Issue :
Preprints
Database :
Supplemental Index
Journal :
Transplantation and Cellular Therapy
Publication Type :
Periodical
Accession number :
ejs57046282
Full Text :
https://doi.org/10.1016/j.jtct.2021.07.001