Back to Search
Start Over
Reactivation of the tumor suppressor PTEN by mRNA nanoparticles enhances antitumor immunity in preclinical models
- Source :
- Science Translational Medicine; June 2021, Vol. 13 Issue: 599 peaba9772
- Publication Year :
- 2021
-
Abstract
- The restoration of tumor suppressor PTEN by synthetic mRNA nanoparticles sensitizes Pten-null or mutated tumors to immune checkpoint blockade therapy.
Details
- Language :
- English
- ISSN :
- 19466234 and 19466242
- Volume :
- 13
- Issue :
- 599
- Database :
- Supplemental Index
- Journal :
- Science Translational Medicine
- Publication Type :
- Periodical
- Accession number :
- ejs56916929
- Full Text :
- https://doi.org/10.1126/scitranslmed.aba9772