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Associations between Persistent Inflammation and Oxidative Stress with Neurocognitive Impairment in Long-Term Hodgkin Lymphoma Survivors and Community Controls

Authors :
Williams, AnnaLynn M
Mulrooney, Daniel A.
Liu, Wei
Ehrhardt, Matt J.
Mirzaei Salehabadi, Sedigheh
Panoskaltsis-Mortari, Angela
Srivastava, Deokumar
Yasui, Yutaka
Hudson, Melissa M.
Robison, Leslie L.
Sabin, Noah D
Krull, Kevin R.
Source :
Blood; November 2019, Vol. 134 Issue: 1, Number 1 Supplement 1 p3479-3479, 1p
Publication Year :
2019

Abstract

Background:Long-term survivors of Hodgkin lymphoma (HL) experience neurocognitive impairment despite receiving no CNS-directed therapy, though little is known about the biologic mechanisms underlying this impairment. This study aimed to examine associations between pro-inflammatory and oxidative stress biomarkers with neurocognitive impairment in long-term HL survivors.

Details

Language :
English
ISSN :
00064971 and 15280020
Volume :
134
Issue :
1, Number 1 Supplement 1
Database :
Supplemental Index
Journal :
Blood
Publication Type :
Periodical
Accession number :
ejs56889127
Full Text :
https://doi.org/10.1182/blood-2019-126041