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A Pilot Study of CX-01 with Azacitidine for Treatment of Hypomethylating Agent-Refractory AML and MDS

Authors :
Huselton, Eric
Cashen, Amanda F.
DiPersio, John F
Jacoby, Meagan
Pusic, Iskra
Romee, Rizwan
Uy, Geoffrey L.
Westervelt, Peter
Source :
Blood; December 2017, Vol. 130 Issue: 1, Number 1 Supplement 1 p5067-5067, 1p
Publication Year :
2017

Abstract

Hypomethylating agents are standard first line therapy for older patients with AML and MDS. While these agents can prolong overall survival and disease free survival, they are not curative and only result in a complete response in about 20-25% of patients. For patients that fail these agents, there are no standard treatment options and overall survival is short at 4-6 months.

Details

Language :
English
ISSN :
00064971 and 15280020
Volume :
130
Issue :
1, Number 1 Supplement 1
Database :
Supplemental Index
Journal :
Blood
Publication Type :
Periodical
Accession number :
ejs56863973
Full Text :
https://doi.org/10.1182/blood.V130.Suppl_1.5067.5067