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High Intratumoral Galectin-1 Is Associated with Adverse Outcome in ALK-Negative, CD30-Positive Peripheral T-Cell Lymphomas

Authors :
Holst, Johanne Marie
Ludvigsen, Maja
Dutoit, Stephen
Bendix, Knud
Plesner, Trine Lindhardt
Noergaard, Peter
Møller, Michael Boe
Steiniche, Torben
Rabinovich, Gabriel
d'Amore, Francesco
Pedersen, Martin Bjerregård
Source :
Blood; December 2017, Vol. 130 Issue: 1, Number 1 Supplement 1 p4079-4079, 1p
Publication Year :
2017

Abstract

Galectin-1 (Gal-1) has been associated with prognosis in several cancers including lymphomas. CD30-dependent cell signaling mediated by Gal-1 has been proposed in CD30-positive lymphomas and cell lines. Still, Gal-1 expression has not been systematically assessed as a possible prognosticator in nodal peripheral T-cell lymphomas (PTCL).

Details

Language :
English
ISSN :
00064971 and 15280020
Volume :
130
Issue :
1, Number 1 Supplement 1
Database :
Supplemental Index
Journal :
Blood
Publication Type :
Periodical
Accession number :
ejs56857564
Full Text :
https://doi.org/10.1182/blood.V130.Suppl_1.4079.4079