Back to Search
Start Over
Select Peripheral Blood Cytokine Levels Are Associated with Survival in Pediatric Acute Myeloid Leukemia
- Source :
- Blood; December 2017, Vol. 130 Issue: 1, Number 1 Supplement 1 p2690-2690, 1p
- Publication Year :
- 2017
-
Abstract
- Background: Risk stratification for pediatric AML currently relies on response to therapy and a small number of prognostic genetic factors. With these limited criteria, approximately 75% of children are initially classified as being at a lower risk (LR) of relapse. However, 30% of LR patients relapse, and achieving a second remission is often quite difficult. Therefore, there is an urgent need improve risk stratification in pediatric AML. Cytokine levels have been shown to predict outcome in adult AML but have not been extensively studied in pediatric AML, in part due to lack of available samples. We utilized a unique repository of diagnostic peripheral blood (PB) plasma from pediatric AML patients to quantify cytokine levels and determine associations with outcome.
Details
- Language :
- English
- ISSN :
- 00064971 and 15280020
- Volume :
- 130
- Issue :
- 1, Number 1 Supplement 1
- Database :
- Supplemental Index
- Journal :
- Blood
- Publication Type :
- Periodical
- Accession number :
- ejs56856234
- Full Text :
- https://doi.org/10.1182/blood.V130.Suppl_1.2690.2690