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Genomic Profiling of Blast Phase in Philadelphia-Negative Myeloproliferative Neoplasms

Authors :
Roncoroni, Elisa
Milosevic Feenstra, Jelena D.
Rumi, Elisa
Pietra, Daniela
Ferretti, Virginia Valeria
Bellini, Marta
Cavalloni, Chiara
Casetti, Ilaria Carola
Jäger, Roland
Bogner, Edith
Ciboddo, Michele
Zappasodi, Patrizia
Picone, Cristina
Vanelli, Laura
Astori, Cesare
Kralovics, Robert
Cazzola, Mario
Source :
Blood; December 2017, Vol. 130 Issue: 1, Number 1 Supplement 1 p1652-1652, 1p
Publication Year :
2017

Abstract

BackgroundClassic Ph-negative myeloproliferative neoplasms (MPN) include essential thrombocythemia (ET), polycythemia vera (PV) and primary myelofibrosis (PMF). Clonal evolution can lead MPN patients in chronic phase (CP) to developacute myeloid leukemia (AML), called blast phase (BP), a rare and late event in the natural history of MPN.

Details

Language :
English
ISSN :
00064971 and 15280020
Volume :
130
Issue :
1, Number 1 Supplement 1
Database :
Supplemental Index
Journal :
Blood
Publication Type :
Periodical
Accession number :
ejs56811987
Full Text :
https://doi.org/10.1182/blood.V130.Suppl_1.1652.1652