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Genetic and Metabolic Determinants of Methotrexate Induced Mucositis in Pediatric Acute Lymphoblastic Leukemia
- Source :
- Blood; December 2014, Vol. 124 Issue: 21 p939-939, 1p
- Publication Year :
- 2014
-
Abstract
- Introduction:Methotrexate (MTX) is an important and effective chemotherapeutic drug in the treatment of pediatric acute lymphoblastic leukemia (ALL). However MTX can induce toxicity, which can lead to amendments of treatment and subsequent impaired survival. The aim of this study was to identify metabolic and genetic determinants of MTX toxicity.
Details
- Language :
- English
- ISSN :
- 00064971 and 15280020
- Volume :
- 124
- Issue :
- 21
- Database :
- Supplemental Index
- Journal :
- Blood
- Publication Type :
- Periodical
- Accession number :
- ejs56778505
- Full Text :
- https://doi.org/10.1182/blood.V124.21.939.939