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CD84: A Potential Novel Therapeutic Target in Multiple Myeloma
- Source :
- Blood; November 2018, Vol. 132 Issue: 1, Number 1 Supplement 1 p1924-1924, 1p
- Publication Year :
- 2018
-
Abstract
- Introduction:Multiple Myeloma (MM) cell survival strictly depends on the interaction with multiple cell types in the bone marrow (BM), collectively referred to as the MM microenvironment (MM-ME). CD84 (SLAMF5) belongs to the signaling lymphocyte activation molecule family of immunoreceptors; previous data from our group have shown that CD84 mediates malignant B cells and their ME (Marom et al.2017); however, its role within the MM-ME has not yet been investigated.
Details
- Language :
- English
- ISSN :
- 00064971 and 15280020
- Volume :
- 132
- Issue :
- 1, Number 1 Supplement 1
- Database :
- Supplemental Index
- Journal :
- Blood
- Publication Type :
- Periodical
- Accession number :
- ejs56584582
- Full Text :
- https://doi.org/10.1182/blood-2018-99-119655