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Changes in in-hospital mortality in the first wave of COVID-19: a multicentre prospective observational cohort study using the WHO Clinical Characterisation Protocol UK

Authors :
Docherty, Annemarie B
Mulholland, Rachel H
Lone, Nazir I
Cheyne, Christopher P
De Angelis, Daniela
Diaz-Ordaz, Karla
Donegan, Cara
Drake, Thomas M
Dunning, Jake
Funk, Sebastian
García-Fiñana, Marta
Girvan, Michelle
Hardwick, Hayley E
Harrison, Janet
Ho, Antonia
Hughes, David M
Keogh, Ruth H
Kirwan, Peter D
Leeming, Gary
Nguyen Van-Tam, Jonathan S
Pius, Riinu
Russell, Clark D
Spencer, Rebecca G
Tom, Brian DM
Turtle, Lance
Openshaw, Peter JM
Baillie, J Kenneth
Harrison, Ewen M
Semple, Malcolm G
Baillie, J Kenneth
Semple, Malcolm G
Openshaw, Peter JM
Carson, Gail
Alex, Beatrice
Bach, Benjamin
Barclay, Wendy S
Bogaert, Debby
Chand, Meera
Cooke, Graham S
Docherty, Annemarie B
Dunning, Jake
da Silva Filipe, Ana
Fletcher, Tom
Green, Christopher A
Harrison, Ewen M
Hiscox, Julian A
Ho, Antonia YW
Horby, Peter W
Ijaz, Samreen
Khoo, Say
Klenerman, Paul
Law, Andrew
Lim, Wei Shen
Mentzer, Alexander J
Merson, Laura
Meynert, Alison M
Noursadeghi, Mahdad
Moore, Shona C
Palmarini, Massimo
Paxton, William A
Pollakis, Georgios
Price, Nicholas
Rambaut, Andrew
Robertson, David L
Russell, Clark D
Sancho-Shimizu, Vanessa
Scott, Janet T
de Silva, Thushan
Sigfrid, Louise
Solomon, Tom
Sriskandan, Shiranee
Stuart, David
Summers, Charlotte
Tedder, Richard S
Thomson, Emma C
Thompson, AA Roger
Thwaites, Ryan S
Turtle, Lance CW
Gupta, Rishi K
Palmieri, Carlo
Zambon, Maria
Hardwick, Hayley
Donohue, Chloe
Lyons, Ruth
Griffiths, Fiona
Oosthuyzen, Wilna
Norman, Lisa
Pius, Riinu
Drake, Thomas M
Fairfield, Cameron J
Knight, Stephen R
Mclean, Kenneth A
Murphy, Derek
Shaw, Catherine A
Dalton, Jo
Girvan, Michelle
Saviciute, Egle
Roberts, Stephanie
Harrison, Janet
Marsh, Laura
Connor, Marie
Halpin, Sophie
Jackson, Clare
Gamble, Carrol
Leeming, Gary
Law, Andrew
Wham, Murray
Clohisey, Sara
Hendry, Ross
Scott-Brown, James
Greenhalf, William
Shaw, Victoria
McDonald, Sarah E
Keating, Seán
Ahmed, Katie A
Armstrong, Jane A
Ashworth, Milton
Asiimwe, Innocent G
Bakshi, Siddharth
Barlow, Samantha L
Booth, Laura
Brennan, Benjamin
Bullock, Katie
Catterall, Benjamin WA
Clark, Jordan J
Clarke, Emily A
Cole, Sarah
Cooper, Louise
Cox, Helen
Davis, Christopher
Dincarslan, Oslem
Dunn, Chris
Dyer, Philip
Elliott, Angela
Evans, Anthony
Finch, Lorna
Fisher, Lewis WS
Foster, Terry
Garcia-Dorival, Isabel
Greenhalf, William
Gunning, Philip
Hartley, Catherine
Jensen, Rebecca L
Jones, Christopher B
Jones, Trevor R
Khandaker, Shadia
King, Katharine
Kiy, Robyn T
Koukorava, Chrysa
Lake, Annette
Lant, Suzannah
Latawiec, Diane
Lavelle-Langham, Lara
Lefteri, Daniella
Lett, Lauren
Livoti, Lucia A
Mancini, Maria
McDonald, Sarah
McEvoy, Laurence
McLauchlan, John
Metelmann, Soeren
Miah, Nahida S
Middleton, Joanna
Mitchell, Joyce
Moore, Shona C
Murphy, Ellen G
Penrice-Randal, Rebekah
Pilgrim, Jack
Prince, Tessa
Reynolds, Will
Ridley, P. Matthew
Sales, Debby
Shaw, Victoria E
Shears, Rebecca K
Small, Benjamin
Subramaniam, Krishanthi S
Szemiel, Agnieska
Taggart, Aislynn
Tanianis-Hughes, Jolanta
Thomas, Jordan
Trochu, Erwan
van Tonder, Libby
Wilcock, Eve
Zhang, J. Eunice
Flaherty, Lisa
Maziere, Nicole
Cass, Emily
Doce Carracedo, Alejandra
Carlucci, Nicola
Holmes, Anthony
Massey, Hannah
Murphy, Lee
Wrobel, Nicola
McCafferty, Sarah
Morrice, Kirstie
MacLean, Alan
Adeniji, Kayode
Agranoff, Daniel
Agwuh, Ken
Ail, Dhiraj
Aldera, Erin L
Alegria, Ana
Angus, Brian
Ashish, Abdul
Atkinson, Dougal
Bari, Shahedal
Barlow, Gavin
Barnass, Stella
Barrett, Nicholas
Bassford, Christopher
Basude, Sneha
Baxter, David
Beadsworth, Michael
Bernatoniene, Jolanta
Berridge, John
Best, Nicola
Bothma, Pieter
Chadwick, David
Brittain-Long, Robin
Bulteel, Naomi
Burden, Tom
Burtenshaw, Andrew
Caruth, Vikki
Chadwick, David
Chambler, Duncan
Chee, Nigel
Child, Jenny
Chukkambotla, Srikanth
Clark, Tom
Collini, Paul
Cosgrove, Catherine
Cupitt, Jason
Cutino-Moguel, Maria-Teresa
Dark, Paul
Dawson, Chris
Dervisevic, Samir
Donnison, Phil
Douthwaite, Sam
DuRand, Ingrid
Dushianthan, Ahilanadan
Dyer, Tristan
Evans, Cariad
Eziefula, Chi
Fegan, Chrisopher
Finn, Adam
Fullerton, Duncan
Garg, Sanjeev
Garg, Sanjeev
Garg, Atul
Gkrania-Klotsas, Effrossyni
Godden, Jo
Goldsmith, Arthur
Graham, Clive
Hardy, Elaine
Hartshorn, Stuart
Harvey, Daniel
Havalda, Peter
Hawcutt, Daniel B
Hobrok, Maria
Hodgson, Luke
Hormis, Anil
Jacobs, Michael
Jain, Susan
Jennings, Paul
Kaliappan, Agilan
Kasipandian, Vidya
Kegg, Stephen
Kelsey, Michael
Kendall, Jason
Kerrison, Caroline
Kerslake, Ian
Koch, Oliver
Koduri, Gouri
Koshy, George
Laha, Shondipon
Laird, Steven
Larkin, Susan
Leiner, Tamas
Lillie, Patrick
Limb, James
Linnett, Vanessa
Little, Jeff
Lyttle, Mark
MacMahon, Michael
MacNaughton, Emily
Mankregod, Ravish
Masson, Huw
Matovu, Elijah
McCullough, Katherine
McEwen, Ruth
Meda, Manjula
Mills, Gary
Minton, Jane
Mirfenderesky, Mariyam
Mohandas, Kavya
Mok, Quen
Moon, James
Moore, Elinoor
Morgan, Patrick
Morris, Craig
Mortimore, Katherine
Moses, Samuel
Mpenge, Mbiye
Mulla, Rohinton
Murphy, Michael
Nagel, Megan
Nagarajan, Thapas
Nelson, Mark
O'Shea, Matthew K
Otahal, Igor
Ostermann, Marlies
Pais, Mark
Panchatsharam, Selva
Papakonstantinou, Danai
Paraiso, Hassan
Patel, Brij
Pattison, Natalie
Pepperell, Justin
Peters, Mark
Phull, Mandeep
Pintus, Stefania
Singh Pooni, Jagtur
Post, Frank
Price, David
Prout, Rachel
Rae, Nikolas
Reschreiter, Henrik
Reynolds, Tim
Richardson, Neil
Roberts, Mark
Roberts, Devender
Rose, Alistair
Rousseau, Guy
Ryan, Brendan
Saluja, Taranprit
Shah, Aarti
Shanmuga, Prad
Sharma, Anil
Shawcross, Anna
Sizer, Jeremy
Shankar-Hari, Manu
Smith, Richard
Snelson, Catherine
Spittle, Nick
Staines, Nikki
Stambach, Tom
Stewart, Richard
Subudhi, Pradeep
Szakmany, Tamas
Tatham, Kate
Thomas, Jo
Thompson, Chris
Thompson, Robert
Tridente, Ascanio
Tupper-Carey, Darell
Twagira, Mary
Ustianowski, Andrew
Vallotton, Nick
Vincent-Smith, Lisa
Visuvanathan, Shico
Vuylsteke, Alan
Waddy, Sam
Wake, Rachel
Walden, Andrew
Welters, Ingeborg
Whitehouse, Tony
Whittaker, Paul
Whittington, Ashley
Papineni, Padmasayee
Wijesinghe, Meme
Williams, Martin
Wilson, Lawrence
Sarah, Sarah
Winchester, Stephen
Wiselka, Martin
Wolverson, Adam
Wooton, Daniel G
Workman, Andrew
Yates, Bryan
Young, Peter
Source :
The Lancet Respiratory Medicine; July 2021, Vol. 9 Issue: 7 p773-785, 13p
Publication Year :
2021

Abstract

Mortality rates in hospitalised patients with COVID-19 in the UK appeared to decline during the first wave of the pandemic. We aimed to quantify potential drivers of this change and identify groups of patients who remain at high risk of dying in hospital.

Details

Language :
English
ISSN :
22132600 and 22132619
Volume :
9
Issue :
7
Database :
Supplemental Index
Journal :
The Lancet Respiratory Medicine
Publication Type :
Periodical
Accession number :
ejs56325509
Full Text :
https://doi.org/10.1016/S2213-2600(21)00175-2