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A Fluorescent Intercalator Displacement Assay for Establishing DNA Binding Selectivity and Affinity
- Source :
- Accounts of Chemical Research; January 2004, Vol. 37 Issue: 1 p61-69, 9p
- Publication Year :
- 2004
-
Abstract
- A summary of the qualitative and quantitative elements of a fluorescent intercalator displacement (FID) assay useful for establishing the DNA binding selectivity, affinity, stoichiometry, and binding site size and distinguishing modes of DNA binding is provided.
Details
- Language :
- English
- ISSN :
- 00014842 and 15204898
- Volume :
- 37
- Issue :
- 1
- Database :
- Supplemental Index
- Journal :
- Accounts of Chemical Research
- Publication Type :
- Periodical
- Accession number :
- ejs5603953