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Antibiotic Susceptibility of Clinical Burkholderia pseudomalleiIsolates in Northeast Thailand from 2015 to 2018 and the Genomic Characterization of β-Lactam-Resistant Isolates

Authors :
Hii, Shirley Yi Fen
Tandhavanant, Sarunporn
Phunpang, Rungnapa
Ekchariyawat, Peeraya
Saiprom, Natnaree
Chewapreecha, Claire
Seng, Rathanin
Thiansukhon, Ekkachai
Morakot, Chumpol
Sangsa, Narongchai
Chayangsu, Sunee
Chuananont, Somchai
Tanwisaid, Kittisak
Silakun, Wirayut
Buasi, Noppol
Chaisuksant, Seksan
Hompleum, Tanin
Chetchotisakd, Ploenchan
Day, Nicholas P. J.
Chantratita, Wasun
Lertmemongkolchai, Ganjana
West, T. Eoin
Chantratita, Narisara
Source :
Antimicrobial Agents and Chemotherapy; 2021, Vol. 65 Issue: 5 pe02230-20-e02230-20, 200220791p
Publication Year :
2021

Abstract

Melioidosis is an often fatal infection in tropical regions caused by an environmental bacterium, Burkholderia pseudomallei. Current recommended melioidosis treatment requires intravenous β-lactam antibiotics such as ceftazidime (CAZ), meropenem (MEM), or amoxicillin-clavulanic acid (AMC) and oral trimethoprim-sulfamethoxazole.

Details

Language :
English
ISSN :
00664804 and 10986596
Volume :
65
Issue :
5
Database :
Supplemental Index
Journal :
Antimicrobial Agents and Chemotherapy
Publication Type :
Periodical
Accession number :
ejs55876229
Full Text :
https://doi.org/10.1128/AAC.02230-20