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Phytic acid. A natural antioxidant.

Authors :
Graf, E
Empson, K L
Eaton, J W
Source :
Journal of Biological Chemistry; August 1987, Vol. 262 Issue: 24 p11647-11650, 4p
Publication Year :
1987

Abstract

The catalysis by iron of radical formation and subsequent oxidative damage has been well documented. Although many iron-chelating agents potentiate reactive oxygen formation and lipid peroxidation, phytic acid (abundant in edible legumes, cereals, and seeds) forms an iron chelate which greatly accelerates Fe2+-mediated oxygen reduction yet blocks iron-driven hydroxyl radical generation and suppresses lipid peroxidation. Furthermore, high concentrations of phytic acid prevent browning and putrefaction of various fruits and vegetables by inhibiting polyphenol oxidase. These observations indicate an important antioxidant function for phytate in seeds during dormancy and suggest that phytate may be a substitute for presently employed preservatives, many of which pose potential health hazards.

Details

Language :
English
ISSN :
00219258 and 1083351X
Volume :
262
Issue :
24
Database :
Supplemental Index
Journal :
Journal of Biological Chemistry
Publication Type :
Periodical
Accession number :
ejs55781195
Full Text :
https://doi.org/10.1016/S0021-9258(18)60858-0