Prospective Randomized Study of Advance Directives in Allogeneic Hematopoietic Cell Transplantation Recipients

•Our study represents one of the only published randomized controlled trials on an advance care planning (ACP) intervention for patients undergoing allogeneic hematopoietic cell transplantation.•Patients were randomized to the traditional state advanced directive (AD) and a novel Stanford Letter AD.•Both groups in the study had a high AD completion rate, much higher than that reported historically elsewhere and at our own institution.•Incorporating ACP education and reminders throughout the transplantation process can increase AD completion rates.