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Assessment of Piperacillin-Tazobactam-Meropenem Synergy against Serine Carbapenemase-Producing EnterobacteralesUsing Time-Kill Assays

Authors :
Lawandi, Alexander
Leite, Gleice C.
Cheng, Matthew P.
Lefebvre, Brigitte
Longtin, Jean
Lee, Todd C.
Source :
Antimicrobial Agents and Chemotherapy; February 2021, Vol. 65 Issue: 4
Publication Year :
2021

Abstract

Synergy between piperacillin-tazobactam and meropenem against KPC-producing Klebsiella pneumoniaewas recently demonstrated. We sought to test the combination against a broader range of serine carbapenemase producers.

Details

Language :
English
ISSN :
00664804 and 10986596
Volume :
65
Issue :
4
Database :
Supplemental Index
Journal :
Antimicrobial Agents and Chemotherapy
Publication Type :
Periodical
Accession number :
ejs55596621
Full Text :
https://doi.org/10.1128/AAC.02317-20