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Analysis of Staphylococcus aureusTranscriptome in Pediatric Soft Tissue Abscesses and Comparison to Murine Infections

Authors :
Moffitt, K.
Cheung, E.
Yeung, T.
Stamoulis, C.
Malley, R.
Source :
Infection and Immunity; 2021, Vol. 89 Issue: 4 pe00715-20-e00715-20, 200070806p
Publication Year :
2021

Abstract

A comprehensive understanding of how Staphylococcus aureusadapts to cause infections in humans can inform development of diagnostic, therapeutic, and preventive approaches. Expression analysis of clinical strain libraries depicts in vitroconditions that differ from those in human infection, but low bacterial burden and the requirement for reverse transcription or nucleic acid amplification complicate such analyses of bacteria causing human infection.

Details

Language :
English
ISSN :
00199567 and 10985522
Volume :
89
Issue :
4
Database :
Supplemental Index
Journal :
Infection and Immunity
Publication Type :
Periodical
Accession number :
ejs55587879
Full Text :
https://doi.org/10.1128/IAI.00715-20