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Gene–environment correlations and causal effects of childhood maltreatment on physical and mental health: a genetically informed approach

Authors :
Warrier, Varun
Kwong, Alex S F
Luo, Mannan
Dalvie, Shareefa
Croft, Jazz
Sallis, Hannah M
Baldwin, Jessie
Munafò, Marcus R
Nievergelt, Caroline M
Grant, Andrew J
Burgess, Stephen
Moore, Tyler M
Barzilay, Ran
McIntosh, Andrew
van IJzendoorn, Marinus H
Cecil, Charlotte A M
Source :
The Lancet Psychiatry; May 2021, Vol. 8 Issue: 5 p373-386, 14p
Publication Year :
2021

Abstract

Childhood maltreatment is associated with poor mental and physical health. However, the mechanisms of gene–environment correlations and the potential causal effects of childhood maltreatment on health are unknown. Using genetics, we aimed to delineate the sources of gene–environment correlation for childhood maltreatment and the causal relationship between childhood maltreatment and health.

Details

Language :
English
ISSN :
22150366
Volume :
8
Issue :
5
Database :
Supplemental Index
Journal :
The Lancet Psychiatry
Publication Type :
Periodical
Accession number :
ejs55583277
Full Text :
https://doi.org/10.1016/S2215-0366(20)30569-1