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Phospholipid Metabolism Is Associated with Time to HIV Rebound upon Treatment Interruption

Authors :
Giron, Leila B.
Papasavvas, Emmanouil
Yin, Xiangfan
Goldman, Aaron R.
Tang, Hsin-Yao
Palmer, Clovis S.
Landay, Alan L.
Li, Jonathan Z.
Koethe, John R.
Mounzer, Karam
Kostman, Jay R.
Liu, Qin
Montaner, Luis J.
Abdel-Mohsen, Mohamed
Source :
mBio; February 2021, Vol. 12 Issue: 1
Publication Year :
2021

Abstract

The likelihood of HIV rebound after stopping antiretroviral therapy (ART) is a combination of the size of HIV reservoirs that persist despite ART and the host immunological and inflammatory factors that control these reservoirs. Therefore, there is a need to comprehensively understand these host factors to develop a strategy to cure HIV infection and prevent viral rebound post-ART.

Details

Language :
English
ISSN :
21612129 and 21507511
Volume :
12
Issue :
1
Database :
Supplemental Index
Journal :
mBio
Publication Type :
Periodical
Accession number :
ejs55470850
Full Text :
https://doi.org/10.1128/mBio.03444-20