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Hyaluronidase Impairs Neutrophil Function and Promotes Group B StreptococcusInvasion and Preterm Labor in Nonhuman Primates

Authors :
Coleman, Michelle
Armistead, Blair
Orvis, Austyn
Quach, Phoenicia
Brokaw, Alyssa
Gendrin, Claire
Sharma, Kavita
Ogle, Jason
Merillat, Sean
Dacanay, Matthew
Wu, Tsung-Yen
Munson, Jeff
Baldessari, Audrey
Vornhagen, Jay
Furuta, Anna
Nguyen, Shayla
Adams Waldorf, Kristina M.
Rajagopal, Lakshmi
Source :
mBio; February 2021, Vol. 12 Issue: 1
Publication Year :
2021

Abstract

Group B streptococci (GBS) are bacteria that commonly reside in the female lower genital tract as asymptomatic members of the microbiota. However, during pregnancy, GBS can infect tissues at the maternal-fetal interface, leading to preterm birth, stillbirth, or fetal injury.

Details

Language :
English
ISSN :
21612129 and 21507511
Volume :
12
Issue :
1
Database :
Supplemental Index
Journal :
mBio
Publication Type :
Periodical
Accession number :
ejs55470804
Full Text :
https://doi.org/10.1128/mBio.03115-20