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Revisiting the definition of bronchopulmonary dysplasia in premature infants at a single center quaternary neonatal intensive care unit
- Source :
- Journal of Perinatology; April 2021, Vol. 41 Issue: 4 p756-763, 8p
- Publication Year :
- 2021
-
Abstract
- Objective: To compare the incidence of bronchopulmonary dysplasia (BPD) based on the 1988 Vermont Oxford Network (VON) criteria, National Institutes of Health (NIH) 2001 definition, and NIH 2018 definition. Methods: BPD incidence by each definition was compared in premature infants born at a single center between 2016 and 2018. Comorbidities were compared between those with and without BPD according to the newest definition. Results: Among 352 survivors, BPD incidence was significantly different at 9%, 28% and 34% according to VON, NIH 2001 and NIH 2018 definitions, respectively (p< 0.05). According to the newest definition, any grade of BPD was associated with more co-morbidities than those without BPD (P< 0.001). Conclusion: At a center that emphasizes use of early noninvasive respiratory support, the incidence of BPD was significantly higher according to the NIH 2018 definition compared to other two definitions. The relationship between BPD diagnosis and long-term clinical outcomes remains unclear.
Details
- Language :
- English
- ISSN :
- 07438346 and 14765543
- Volume :
- 41
- Issue :
- 4
- Database :
- Supplemental Index
- Journal :
- Journal of Perinatology
- Publication Type :
- Periodical
- Accession number :
- ejs55461715
- Full Text :
- https://doi.org/10.1038/s41372-021-00980-4