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COVID-19 and emerging viral infections: The case for interferon lambda

Authors :
Prokunina-Olsson, Ludmila
Alphonse, Noémie
Dickenson, Ruth E.
Durbin, Joan E.
Glenn, Jeffrey S.
Hartmann, Rune
Kotenko, Sergei V.
Lazear, Helen M.
O’Brien, Thomas R.
Odendall, Charlotte
Onabajo, Olusegun O.
Piontkivska, Helen
Santer, Deanna M.
Reich, Nancy C.
Wack, Andreas
Zanoni, Ivan
Source :
The Journal of Experimental Medicine; May 2020, Vol. 217 Issue: 5 pe20200653-e20200653, 1p
Publication Year :
2020

Abstract

With the first reports on coronavirus disease 2019 (COVID-19), which is caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the scientific community working in the field of type III IFNs (IFN-λ) realized that this class of IFNs could play an important role in this and other emerging viral infections. In this Viewpoint, we present our opinion on the benefits and potential limitations of using IFN-λ to prevent, limit, and treat these dangerous viral infections.

Details

Language :
English
ISSN :
00221007 and 15409538
Volume :
217
Issue :
5
Database :
Supplemental Index
Journal :
The Journal of Experimental Medicine
Publication Type :
Periodical
Accession number :
ejs55325627
Full Text :
https://doi.org/10.1084/jem.20200653