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Onset of effect and impact on health-related quality of life, exacerbation rate, lung function, and nasal polyposis symptoms for patients with severe eosinophilic asthma treated with benralizumab (ANDHI): a randomised, controlled, phase 3b trial
Authors :
Harrison, Tim W Chanez, Pascal Menzella, Francesco Canonica, Giorgio Walter Louis, Renaud Cosio, Borja G Lugogo, Njira L Mohan, Arjun Burden, Annie McDermott, Lawrence Garcia Gil, Esther Zangrilli, James G Pohl, Wolfgang Voves, Robert Deschampheleire, Maud Louis, Renaud Martinot, Jean-Benoit Peché, Rudi Chapman, Kenneth Cheema, Amarjit Dorscheid, Delbert FitzGerald, J. Mark Gagnon, Remi Killorn, William Patrick Olivenstein, Ronald Philteos, George Ramsey, Clare Rolf, J. Douglass Walker, Brandie Hilberg, Ole Skjold, Tina Titlestad, Ingrid Hakulinen, Auli Kilpeläinen, Maritta Ben Hayoun, Michèle Bonniaud, Philippe Bourdin, Arnaud Chanez, Pascal De Blay, Frédéric Deslee, Gaëtan Devouassoux, Gilles Didier, Alain Douadi, Youcef Fry, Stéphanie Garcia, Gilles Girodet, Pierre-Olivier Leroyer, Christophe Magnan, Antoine Mahay, Guillaume Nocent, Cécilia Pison, Christophe Roux, Pauline-Marie Taillé, Camille Tiotiu, Juliana-Angelica Beck, Ekkehard Jandl, Margret Kaehler, Christian Kässner, Frank Koesters, Frank Kronsbein, Juliane Schaum, Thomas Schulz, Christian Skowasch, Dirk Taube, Christian Welte, Tobias de Roux, Andrés Beghé, Bianca Blasi, Francesco Canonica, Giorgio Walter Carpagnano, Giovanna Caruso, Cristiano Corsico, Angelo Guido Constantino, Elio Crimi, Nunzio Maestrelli, Piero Menzella, Francesco Milanese, Manlio Papi, Alberto Pelaia, Girolamo Pini, Laura Santus, Pierachille Savi, Eleonora Scichilone, Nicola Senna, Gianenrico Spadaro, Giuseppe Vaghi, Adriano Gans, Steven Hölters, Jurgen Langeveld, B. Pieters, Willem Staaks, G.H.A. van Veen, Ilonka van den Berg, J.W.K. Einvik, Gunnar Lehmann, Sverre Ali García, Ismael Almonacid, Carlos Bobolea, Irina Campo Mozo, Paloma de Luiz, Gustavo Domingo Ribas, Christian Echave-Sustaeta María-Tomé, José María García Rivero, Juan Luis García-Cosío Piqueras, Borja Gómez-Bastero Fernández, Ana González Pérez, Ruperto Henríquez Santa, Aythamy Martínez Rivera, Carlos Muñoz Gall, Xavier Ramos, Jacinto Gregorio Soto Campos, Jose Vidal Pan, Carmen Stenfors, Nikolai Tunsäter, Alf Vinge, Ines Chaudhuri, Rekha Harrison, Timothy Mansur, Adel Nasser, Shuaib Nordstrom, Monica Pfeffer, Paul Saralaya, Dinesh Short, Philip Adlakha, Arun Alpan, Oral Averill, Francis Badhwar, Anil Bardelas, Jose Baxter, Barbara Bensch, George Berger, William Bernstein, Jonathan Bridges, Tracy Brimeyer, Ryan Calhoun, William Campbell, Edward Cherry, William Brett Chupp, Geoffrey Clore, Lee Cohn, John Cole, Jeremy Condemi, John Cury, James Davis, Benjamin DeLeon, Samuel Delacruz, Luis Diaz, Joseph Erb, David Eziri, Emeka Fakih, Faisal Fiedler, Douglas Fost, David Fritz, Stephen Gonzalez, Erika Goodman, Brad Gottlieb, Peter Gottschlich, Gregory Gower, Richard Hajal, Rizan Harris, James Heidarian-Raissy, Hengameh Heyder, Albrecht Hill, David Holguin, Fernando Hussain, Iftikhar Illowite, Jonathan Jacobs, Joshua Jarratt, Mikell Kaiser, Harold Kao, Neil Kashyap, Ravindra Kaufman, David Kent, Edward Kim, Kenneth Klein, Ryan Kraft, Monica Kono, Ritsu Kureishy, Shahrukh Leflein, Jeffrey Leong, Mila Li, Huamin Lin, Robert Lugogo, Njira Marcus, Michael Maselli Caceres, Diego Jose Mehta, Vinay Mello, Curtis Millard, Mark Milstone, Aaron Mohan, Arjun Moore, Wendy Moss, Mark Mumneh, Nayla O'Brien, Thomas Ostransky, David Palumbo, Michael Parikh, Purvi Parikh, Sudhir Patel, Amit Perez, Guido Pleskow, Warren Prenner, Bruce Puppala, Dileep Ramey, John Reibman, Joan Reyes, Ramon Robinette, Emory Rodicio, Ileana Ryan, Stephen Sekhsaria, Sudhir Sigal, Barry Sikand, Vinay Soong, Weily Spangenthal, Selwyn St. John, Roy Steven, Gary Subramaniam, Vijay Sumino, Kaharu Sztejman, Eric Tan, Ricardo A. Tanus, Tonny Thompson, Charles Thornblade, Carl Villareal, Manuel Wenzel, Sally Zafra, Heidi Ziedalski, Tomasz
Source :
The Lancet Respiratory Medicine; March 2021, Vol. 9 Issue: 3 p260-274, 15p
Publication Year :
2021
Abstract
ANDHI was done to assess the efficacy of benralizumab, including onset of effect and impact on health-related quality of life (HRQOL), exacerbation rate, lung function, and nasal polyposis symptoms.
Details
Language :
English
ISSN :
22132600 and 22132619
Volume :
9
Issue :
3
Database :
Supplemental Index
Journal :
The Lancet Respiratory Medicine
Publication Type :
Periodical
Accession number :
ejs55193320
Full Text :
https://doi.org/10.1016/S2213-2600(20)30414-8