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Alveolar Soft Part Sarcoma of Uterine Corpus in a Young Female: A Case Report With Review of Literature
- Source :
- International Journal of Gynecological Pathology; 20240101, Issue: Preprints
- Publication Year :
- 2024
-
Abstract
- Alveolar soft part sarcoma (ASPS) is a rare soft tissue sarcoma, often occurs in adolescents and young adults with a particular predilection for the deep soft tissue of extremities. Occurrence of ASPS in the female genital tract is very uncommon and poses a significant diagnostic challenge. A case of ASPS of the uterine corpus is described in a young unmarried female, who presented to the out-patient clinic of our Institute with complaints of abnormal uterine bleeding for the past 9 mo. She was being treated with oral contraceptive pills, progesterone and tranexamic acid. Following radiological imaging and hysteroscopy, a therapeutic curettage of the lesion was done. The histopathologic features raised a differential diagnosis of a myriad of morphologic mimickers. The diagnosis was clinched by exclusion of mimickers by relevant immunohistochemical markers and strong nuclear expression of TFE3 on immunohistochemistry. The patient is on regular follow-up with oral contraceptives and antifibrinolytic medication. Despite being infrequent at this location, ASPS should be kept in differential diagnosis in young females presenting with abnormal uterine bleeding.
Details
- Language :
- English
- ISSN :
- 02771691 and 15387151
- Issue :
- Preprints
- Database :
- Supplemental Index
- Journal :
- International Journal of Gynecological Pathology
- Publication Type :
- Periodical
- Accession number :
- ejs55044611
- Full Text :
- https://doi.org/10.1097/PGP.0000000000000700