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Alemtuzumab outcomes by age: Post hoc analysis from the randomized CARE-MS studies over 8 years

Authors :
Bass, Ann D.
Arroyo, Rafael
Boster, Aaron L.
Boyko, Alexey N.
Eichau, Sara
Ionete, Carolina
Limmroth, Volker
Navas, Carlos
Pelletier, Daniel
Pozzilli, Carlo
Ravenscroft, Jennifer
Sousa, Livia
Tintoré, Mar
Uitdehaag, Bernard M.J.
Baker, Darren P.
Daizadeh, Nadia
Choudhry, Zia
Rog, David
Source :
Multiple Sclerosis and Related Disorders; April 2021, Vol. 49 Issue: 1
Publication Year :
2021

Abstract

•Across age groups, alemtuzumab efficacy was greater than SC IFNB-1a over 2 years.•Alemtuzumab maintained clinical and MRI efficacy over 8 years in all age groups.•Age-related increases in serious infections, malignancies, and deaths were observed.

Details

Language :
English
ISSN :
22110348
Volume :
49
Issue :
1
Database :
Supplemental Index
Journal :
Multiple Sclerosis and Related Disorders
Publication Type :
Periodical
Accession number :
ejs54937370
Full Text :
https://doi.org/10.1016/j.msard.2020.102717