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Costameric integrin and sarcoglycan protein levels are altered in a Drosophilamodel for Limb-girdle muscular dystrophy type 2H
- Source :
- Molecular Biology of the Cell; February 2021, Vol. 32 Issue: 3 p260-273, 14p
- Publication Year :
- 2021
-
Abstract
- Expression of human disease-causing LGMD2H alleles in Drosophilacauses muscle degeneration and elevated levels of integrin and sarcoglycan costamere proteins, likely exacerbating disease progression.
Details
- Language :
- English
- ISSN :
- 10591524 and 19394586
- Volume :
- 32
- Issue :
- 3
- Database :
- Supplemental Index
- Journal :
- Molecular Biology of the Cell
- Publication Type :
- Periodical
- Accession number :
- ejs54808760
- Full Text :
- https://doi.org/10.1091/mbc.E20-07-0453