Evaluation of Daily Laurus nobilisTea Consumption on Lipid Profile Biomarkers in Healthy Volunteers

AbstractIntroduction:Laurus nobilisis known in the field of herbal medicine and in vitrostudies that it has beneficial effects such as antibacterial, antifungal, antidiabetes, and anti-inflammatory properties.Objective:We investigated whether L. nobilistea consumption affects the plasma levels of lipid biomarkers in healthy volunteers.Methods:Thirty healthy Tunisian volunteers aged between 20 and 57 years old consumed L. nobilisinfusion, prepared from 5 g of dried L. nobilisleaves in 100 ml boiled water, once a day during 10 days. Plasma concentrations of serum low-density lipoprotein (LDL) cholesterol, triglycerides and HDL (high-density lipoprotein) cholesterol were measured by Beckman Coulter D × 600 analyzer before L. nobilisconsumption and at the end of the experiment.Results:L. nobilistea consumption significantly increased the concentration of HDL cholesterol ([HDL cholesterol] D0= 1.34 ± 0.25 pg/mL, D11=1.42 ± 0.29, p = 0.01). However, a slight decrease that was statistically non-significant in LDL cholesterol and triglycerides levels was observed (p < 0.05).Conclusions:These findings highlight the improving blood lipidic profiles, which means a possible positive effect on reducing the risk of cardiovascular disease of L. nobilistea consumption in healthy volunteers. However, more powerful studies with an extended treatment period are required.