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High-Resolution Solid-State NMR Applied to Polypeptides and Membrane Proteins
- Source :
- Accounts of Chemical Research; November 2003, Vol. 36 Issue: 11 p858-865, 8p
- Publication Year :
- 2003
-
Abstract
- Solid-state NMR provides unique possibilities to study insoluble or noncrystalline molecules at the atomic level. High-resolution conditions can be established by employing magic-angle spinning at ultrahigh magnetic fields. We discuss NMR methods that make use of these experimental improvements and allow for the study of multiply or uniformly [<SUP>13</SUP>C,<SUP>15</SUP>N]-labeled polypeptides and proteins. Recent biophysical applications are reviewed.
Details
- Language :
- English
- ISSN :
- 00014842 and 15204898
- Volume :
- 36
- Issue :
- 11
- Database :
- Supplemental Index
- Journal :
- Accounts of Chemical Research
- Publication Type :
- Periodical
- Accession number :
- ejs5457599