Back to Search Start Over

Carbon-11 acetate as a tracer of myocardial oxygen consumption

Authors :
Klein, Lucas J.
Visser, Frans C.
Knaapen, Paul
Peters, Job H.
Teule, Gerrit J.J.
Visser, Cees A.
Lammertsma, Adriaan A.
Source :
European Journal of Nuclear Medicine and Molecular Imaging; May 2001, Vol. 28 Issue: 5 p651-668, 18p
Publication Year :
2001

Abstract

Estimation of myocardial oxygen consumption (MVO2) and myocardial blood flow (MBF) is important for the understanding of various (patho)physiological mechanisms and diseases. Clearance rates of carbon-11 labelled acetate, determined with positron emission tomography, allow estimation of MVO2on a segmental level and non-invasively. In addition, MBF can be determined from uptake rates. In this review, the background to estimation of MVO2and MBF is discussed, as well as the currently available literature that has used 11C-acetate to estimate MVO2and MBF.

Details

Language :
English
ISSN :
16197070 and 16197089
Volume :
28
Issue :
5
Database :
Supplemental Index
Journal :
European Journal of Nuclear Medicine and Molecular Imaging
Publication Type :
Periodical
Accession number :
ejs544714
Full Text :
https://doi.org/10.1007/s002590000472