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HSP90 expression and early recurrence in gastroenteropancreatic neuroendocrine tumors: Potential for a novel therapeutic target

Authors :
Gamboa, Adriana C.
Ethun, Cecilia G.
Postlewait, Lauren M.
Lopez-Aguiar, Alexandra G.
Zhelnin, Kristen
Krasinskas, Alyssa
El-Rayes, Bassel F.
Russell, Maria C.
Kooby, David A.
Staley, Charles A.
Cardona, Kenneth
Maithel, Shishir K.
Source :
Surgical Oncology; December 2020, Vol. 35 Issue: 1 p460-465, 6p
Publication Year :
2020

Abstract

Heat shock protein (HSP)-90 promotes tumor growth and is overexpressed in many malignancies. HSP90 expression profile and its potential as a therapeutic target in primary and metastatic neuroendocrine tumors (NETs) are not known.

Details

Language :
English
ISSN :
09607404
Volume :
35
Issue :
1
Database :
Supplemental Index
Journal :
Surgical Oncology
Publication Type :
Periodical
Accession number :
ejs54354729
Full Text :
https://doi.org/10.1016/j.suronc.2020.09.018