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Analysis of Time to Complete Response after Defibrotide Initiation in Patients with Hepatic Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome after Hematopoietic Cell Transplantation
- Source :
- Biology of Blood and Marrow Transplantation (Science Direct); 20240101, Issue: Preprints
- Publication Year :
- 2024
-
Abstract
- •We analyzed the time to complete response (CR) or discontinuation due to CR in 3 studies of post-hematopoietic stem cell transplantation hepatic veno-occlusive disease/sinusoidal obstruction syndrome (VOD/SOS).•Complete response to defibrotide occurred beyond 21 days in >50% of patients.•Response occurred after more than 28 days of defibrotide treatment in some patients.•The importance of continuing defibrotide until VOD/SOS resolution is highlighted.
Details
- Language :
- English
- ISSN :
- 10838791 and 15236536
- Issue :
- Preprints
- Database :
- Supplemental Index
- Journal :
- Biology of Blood and Marrow Transplantation (Science Direct)
- Publication Type :
- Periodical
- Accession number :
- ejs54311829
- Full Text :
- https://doi.org/10.1016/j.bbmt.2020.09.008