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Reward Versus Nonreward Sensitivity of the Medial Versus Lateral Orbitofrontal Cortex Relates to the Severity of Depressive Symptoms

Authors :
Xie, Chao
Jia, Tianye
Rolls, Edmund T.
Robbins, Trevor W.
Sahakian, Barbara J.
Zhang, Jie
Liu, Zhaowen
Cheng, Wei
Luo, Qiang
Zac Lo, Chun-Yi
Wang, He
Banaschewski, Tobias
Barker, Gareth J.
Bokde, Arun L.W.
Büchel, Christian
Quinlan, Erin Burke
Desrivières, Sylvane
Flor, Herta
Grigis, Antoine
Garavan, Hugh
Gowland, Penny
Heinz, Andreas
Hohmann, Sarah
Ittermann, Bernd
Martinot, Jean-Luc
Paillère Martinot, Marie-Laure
Nees, Frauke
Orfanos, Dimitri Papadopoulos
Paus, Tomáš
Poustka, Luise
Fröhner, Juliane H.
Smolka, Michael N.
Walter, Henrik
Whelan, Robert
Schumann, Gunter
Feng, Jianfeng
Artiges, Eric
Aydin, Semiha
Banaschewski, Tobias
Barbot, Alexis
Barker, Gareth
Becker, Andreas
Bezivin-Frere, Pauline
Biondo, Francesca
Bokde, Arun
Büchel, Christian
Chu, Congying
Conrod, Patricia
Daedelow, Laura
Dalley, Jeffrey
Desrivieres, Sylvane
Dooley, Eoin
Filippi, Irina
Fillmer, Ariane
Flor, Herta
Fröhner, Juliane
Frouin, Vincent
Garavan, Hugh
Gowland, Penny
Grimmer, Yvonne
Heinz, Andreas
Hohmann, Sarah
Ihlenfeld, Albrecht
Ing, Alex
Isensee, Corinna
Ittermann, Bernd
Jia, Tianye
Lemaitre, Hervé
Lethbridge, Emma
Martinot, Jean-Luc
Millenet, Sabina
Miller, Sarah
Miranda, Ruben
Nees, Frauke
Paillere, Marie-Laure
Papadopoulos, Dimitri
Paus, Tomáš
Pausova, Zdenka
Pentilla, Jani
Poline, Jean-Baptiste
Poustka, Luise
Burke, Erin
Rapp, Michael
Robbins, Trevor
Robert, Gabriel
Rogers, John
Ruggeri, Barbara
Schumann, Gunter
Smolka, Michael
Stringaris, Argyris
van Noort, Betteke
Walter, Henrik
Whelan, Robert
Simon, Roux
Williams, Steve
Zhang, Yuning
Source :
Biological Psychiatry: Cognitive Neuroscience and Neuroimaging; March 2021, Vol. 6 Issue: 3 p259-269, 11p
Publication Year :
2021

Abstract

The orbitofrontal cortex (OFC) is implicated in depression. The hypothesis investigated was whether the OFC sensitivity to reward and nonreward is related to the severity of depressive symptoms.

Details

Language :
English
ISSN :
24519022
Volume :
6
Issue :
3
Database :
Supplemental Index
Journal :
Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
Publication Type :
Periodical
Accession number :
ejs54179972
Full Text :
https://doi.org/10.1016/j.bpsc.2020.08.017