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In VitroActivities of Ravuconazole and Isavuconazole against Dematiaceous Fungi

Authors :
Zheng, Hailin
Song, Nana
Mei, Huan
Dong, Jiacheng
Li, Dongmei
Li, Xiaofang
Liu, Weida
Source :
Antimicrobial Agents and Chemotherapy; July 2020, Vol. 64 Issue: 9
Publication Year :
2020

Abstract

The in vitroactivities of 11 antifungals against 84 dematiaceous fungi were tested. For most tested fungal species, the MIC values of ravuconazole and isavuconazole were lower than those obtained with itraconazole, voriconazole, and posaconazole. Ravuconazole and isavuconazole appear to be more efficient against most dematiaceous fungal infections than the other triazoles. However, some pigmented fungi, such as Bipolaris spiciferaand Veronaea botryosa, remain more susceptible to other triazoles or to echinocandins.

Details

Language :
English
ISSN :
00664804 and 10986596
Volume :
64
Issue :
9
Database :
Supplemental Index
Journal :
Antimicrobial Agents and Chemotherapy
Publication Type :
Periodical
Accession number :
ejs54022366
Full Text :
https://doi.org/10.1128/AAC.00643-20