Cortical abnormalities and identification for first-episode schizophrenia via high-resolution magnetic resonance imaging

Evidence from neuroimaging has implicated abnormal cerebral cortical patterns in schizophrenia. Application of machine learning techniques is required for identifying structural signature reflecting neurobiological substrates of schizophrenia at the individual level. We aimed to develop a method to identify patients with schizophrenia from healthy individuals via the features of cerebral cortex using high-resolution magnetic resonance imaging (MRI).