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Chronic obstructive pulmonary disease and related phenotypes: polygenic risk scores in population-based and case-control cohorts
- Source :
- The Lancet Respiratory Medicine; July 2020, Vol. 8 Issue: 7 p696-708, 13p
- Publication Year :
- 2020
-
Abstract
- Genetic factors influence chronic obstructive pulmonary disease (COPD) risk, but the individual variants that have been identified have small effects. We hypothesised that a polygenic risk score using additional variants would predict COPD and associated phenotypes.
Details
- Language :
- English
- ISSN :
- 22132600 and 22132619
- Volume :
- 8
- Issue :
- 7
- Database :
- Supplemental Index
- Journal :
- The Lancet Respiratory Medicine
- Publication Type :
- Periodical
- Accession number :
- ejs53723789
- Full Text :
- https://doi.org/10.1016/S2213-2600(20)30101-6