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Genomic Analysis of Mycobacterium abscessusComplex Isolates Collected in Ireland between 2006 and 2017

Authors :
Redondo, Natalia
Mok, Simone
Montgomery, Lorraine
Flanagan, Peter R.
McNamara, Eleanor
Smyth, Edmond G.
O'Sullivan, Niamh
Schaffer, Kirsten
Rogers, Thomas R.
Fitzgibbon, Margaret M.
Source :
Journal of Clinical Microbiology; April 2020, Vol. 58 Issue: 7
Publication Year :
2020

Abstract

Members of the Mycobacterium abscessuscomplex (MABC) are multidrug-resistant nontuberculous mycobacteria and cause opportunistic pulmonary infections in individuals with cystic fibrosis (CF). In this study, genomic analysis of MABC isolates was performed to gain greater insights into the epidemiology of circulating strains in Ireland. Whole-genome sequencing (WGS) was performed on 70 MABC isolates that had been referred to the Irish Mycobacteria Reference Laboratory between 2006 and 2017 across nine Irish health care centers.

Details

Language :
English
ISSN :
00951137 and 1098660X
Volume :
58
Issue :
7
Database :
Supplemental Index
Journal :
Journal of Clinical Microbiology
Publication Type :
Periodical
Accession number :
ejs53609176
Full Text :
https://doi.org/10.1128/JCM.00295-20