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Raising the ribosomal repertoire

Authors :
Reinkemeier, Christopher D.
Lemke, Edward A.
Source :
Nature Chemistry; June 2020, Vol. 12 Issue: 6 p503-504, 2p
Publication Year :
2020

Abstract

Three versatile and mutually orthogonal tRNA/aminoacyl-tRNA synthetase pairs have been developed. Collectively, these pairs enable the site-specific incorporation of three different non-canonical amino acids into a protein that can still be terminated faithfully by a natural stop codon.

Details

Language :
English
ISSN :
17554330 and 17554349
Volume :
12
Issue :
6
Database :
Supplemental Index
Journal :
Nature Chemistry
Publication Type :
Periodical
Accession number :
ejs53353398
Full Text :
https://doi.org/10.1038/s41557-020-0476-6