Immunosuppression in Cows following Intramammary Infusion of Mycoplasma bovis

Mycoplasma bovisis a destructive pathogen that causes large economic losses in rearing cattle for beef and dairy worldwide. M. boviscauses suppression of and evades the host immune response; however, the mechanisms of host immune function involved in M. bovismastitis have not been elucidated. The purpose of this study was to elucidate the characteristics of the bovine immune response to mycoplasmal mastitis. We evaluated the responsiveness of the bovine mammary gland following infusion of M. bovis.