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High-Level Carbapenem Resistance in OXA-232-Producing Raoultella ornithinolyticaTriggered by Ertapenem Therapy

Authors :
Iovleva, Alina
Mettus, Roberta T.
McElheny, Christi L.
Griffith, Marissa P.
Mustapha, Mustapha M.
Pasculle, A. William
Shields, Ryan K.
Cooper, Vaughn S.
Doi, Yohei
Source :
Antimicrobial Agents and Chemotherapy; September 2019, Vol. 64 Issue: 1
Publication Year :
2019

Abstract

OXA-232 is an OXA-48-group class D β-lactamase that hydrolyzes expanded-spectrum cephalosporins and carbapenems at low levels. Clinical strains producing OXA-232 are sometimes susceptible to carbapenems, making it difficult to identify them in the clinical microbiology laboratory.

Details

Language :
English
ISSN :
00664804 and 10986596
Volume :
64
Issue :
1
Database :
Supplemental Index
Journal :
Antimicrobial Agents and Chemotherapy
Publication Type :
Periodical
Accession number :
ejs53329451
Full Text :
https://doi.org/10.1128/AAC.01335-19