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The Hypoxia-Inducible Factor-1alpha Is Constitutively Upregulated in TP53 Disrupted CLL Cells: A Potential Target to Overcome Fludarabine Resistance

Authors :
Griggio, Valentina
Vitale, Candida
Riganti, Chiara
Kopecka, Joanna
Dal Bo, Michele
Rossi, Davide
Pozzato, Gabriele
Laurenti, Luca
Zallio, Francesco
Marchetti, Monia
Ruggeri, Marina
Omedè, Paola
Del Poeta, Giovanni
Gattei, Valter
Gaidano, Gianluca
Boccadoro, Mario
Massaia, Massimo
Coscia, Marta
Source :
Blood; December 2015, Vol. 126 Issue: 23 p2925-2925, 1p
Publication Year :
2015

Abstract

Marchetti: GILEAD: Consultancy, Research Funding; JANSSEN: Other: tavel, accomodation, expenses; SANOFI: Membership on an entity's Board of Directors or advisory committees; GILEAD: Other: teaching, Research Funding; NOVARTIS: Research Funding. Gaidano:MorphoSys; Roche; Novartis; GlaxoSmithKline; Amgen; Janssen; Karyopharm: Honoraria, Other: Advisory boards; Celgene: Research Funding. Boccadoro:Sanofi: Consultancy, Membership on an entity's Board of Directors or advisory committees; Celgene: Consultancy, Membership on an entity's Board of Directors or advisory committees; Onyx Pharmaceuticals: Consultancy, Membership on an entity's Board of Directors or advisory committees; Janssen-Cilag: Consultancy, Membership on an entity's Board of Directors or advisory committees. Massaia:Gilead: Research Funding; Janssen: Honoraria; Roche: Honoraria. Coscia:Roche: Honoraria, Other: Advisory board; Mundipharma: Honoraria.

Details

Language :
English
ISSN :
00064971 and 15280020
Volume :
126
Issue :
23
Database :
Supplemental Index
Journal :
Blood
Publication Type :
Periodical
Accession number :
ejs53082627
Full Text :
https://doi.org/10.1182/blood.V126.23.2925.2925