A rare carbapenem-resistant hypervirulent K1/ST1265 Klebsiella pneumoniaewith an untypeable blaKPC-harboured conjugative plasmid

•A rare carbapenem-resistant hypervirulent K1/ST1265 Klebsiella pneumoniaewas analyzed.•The strain carries a blaKPC-harboured conjugative plasmid and a pLVPK-like virulent plasmid.•CR-HvKP strain could be evolved from various types of HvKP strains.•R-M system on plasmids may protect the plasmids from cleavage.•Pernicious CR-HvKP strains pose serious threats to public health.