Overexpression of efflux pump transporter genes and mutations in ERG11pave the way to fluconazole resistance in Candida tropicalis: A study from a North India region

•India has little data on Candida tropicalisdrug resistance mechanisms.•The incidence of acquired resistance among C. tropicalisis of major concern.•Mutations and the overexpression of transporter genes play a vital role in fluconazole resistance.•Evaluation of all possible resistance mechanisms is required for proper treatment outcomes.•The possible role of efflux pump inhibitors (EPIs) in resistance reversal is discussed.